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    New Research Shows Where Women Carry Fat Could Protect Them From Brain Disease

    When it comes to protecting from brain disease, we know a few rules that’ll help us age gracefully: exercise regularly and go easy on the sugar and fats. But a new study has linked the natural fat deposits in female bodies as a key protector against brain disease.

    Not all fat is bad

    Like avocados, not all fats are bad. We know this to be true when looking at our diets: high-fat diets that include pizza and excess animal fats tend to have higher negative outcomes than a diet high in olive oil, fatty seeds and nuts and other plant-based fats.

    But a new study shows that the propensity for women to collect fat in places like their hips, butt and backs of the arms (called subcutaneous fat), could protect against brain disease like dementia and stroke. Males, on the other hand, store fat around major organs in the abdominal region, called visceral adiposity, which promotes inflammation.

    Before, the differences in immune response to brain disease were thought to be down to hormonal discrepancies, but this study offers a new perspective. In ScienceDaily, Alexis M. Stranahan, PhD, neuroscientist in the Department of Neuroscience and Regenerative Medicine at the Medical College of Georgia at Augusta University, said that “When people think about protection in women, their first thought is oestrogen. But we need to get beyond the kind of simplistic idea that every sex difference involves hormone differences and hormone exposure.”

    READ MORE: A New Study Shows That Nightmares Are A Good Predictor Of Future Dementia

    Where you store fat matters

    The study scientists started by inducing obesity in rats, then observing the differences in fat distribution around the body in the males and females. They then noticed that where female rats stored fat correlated with protection against inflammation. They also performed liposuction on the rats before inducing obesity, and were then studied after taking on a high-fat diet, which is known to cause inflammation in the body. The elimination of the fat meant that the rats had less protection against inflammation.

    “When we took subcutaneous fat (fat stored under the skin) out of the equation, all of a sudden the females’ brains start to exhibit inflammation the way that male brains do, and the females gained more visceral fat (fat around the abdominal area),” Stranahan says. “It kind of shunted everything toward that other storage location.” It turns out where the female rats stored fat correlated with a higher level of protection against inflammation, particularly where brain disease is concerned, author’s noted.

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    So, what are the implications for your health?

    Without the liposuction surgery, female rats on a high-fat diet only displayed inflammation similar to the level of male rats after menopause, showing that the fat storage was protective in females before this period. It’s notable that even after liposuction, a high-fat diet still correlated with high levels of inflammation, so stick to a whole foods diet.  

    Stranahan notes that this likely has implications for using the BMI as a benchmark for overall health. “We can’t just say obesity. We have to start talking about where the fat is. That is the critical element here,” Stranahan says. A more accurate reading? Looking at the hip to waist ratio, she says.

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    The bottom line: where fat is stored links to inflammation in the brain. Visceral fat promotes inflammation while subcutaneous fat acts as protection, and high-fat diets are not a good idea to take on (kinda, sorta duh), since they promote inflammation. More

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    A New Study Shows That Nightmares Are A Good Predictor Of Future Dementia

    We spend a third of our lives asleep. And a quarter of our time asleep is spent dreaming. So, for the average person alive in 2022, with a life expectancy of around 73, that clocks in at just over six years of dreaming.

    Yet, given the central role that dreaming plays in our lives, we still know so little about why we dream, how the brain creates dreams, and importantly, what the significance of our dreams might be for our health – especially the health of our brains.

    My latest study, published in The Lancet’s eClinicalMedicine journal, shows that our dreams can reveal a surprising amount of information about our brain health. More specifically, it shows that having frequent bad dreams and nightmares (bad dreams that make you wake up) during middle or older age, may be linked with an increased risk of developing dementia.

    In the study, I analysed data from three large US studies of health and ageing. These included over 600 people aged between 35 and 64, and 2,600 people aged 79 and older.

    All the participants were dementia-free at the start of the study and were followed for an average of nine years for the middle-aged group and five years for the older participants.

    At the beginning of the study (2002-12), the participants completed a range of questionnaires, including one which asked about how often they experienced bad dreams and nightmares.

    I analysed the data to find out whether participants with a higher frequency of nightmares at the beginning of the study were more likely to go on to experience cognitive decline (a fast decline in memory and thinking skills over time) and be diagnosed with dementia.

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    Weekly nightmares

    I found that middle-aged participants who experienced nightmares every week, were four times more likely to experience cognitive decline (a precursor to dementia) over the following decade, while the older participants were twice as likely to be diagnosed with dementia.

    Interestingly, the connection between nightmares and future dementia was much stronger for men than for women. For example, older men who had nightmares every week were five times more likely to develop dementia compared with older men reporting no bad dreams. In women, however, the increase in risk was only 41%. I found a very similar pattern in the middle-aged group.

    Overall, these results suggest frequent nightmares may be one of the earliest signs of dementia, which can precede the development of memory and thinking problems by several years or even decades – especially in men.

    Alternatively, it is also possible that having regular bad dreams and nightmares might even be a cause of dementia.

    Given the nature of this study, it is not possible to be certain which of these theories is correct (though I suspect it is the former). However, regardless of which theory turns out to be true – the major implication of the study remains the same, that is, that having regular bad dreams and nightmares during middle and older age may be linked to an increased risk of developing dementia later in life.

    READ MORE: Are Your Drinking Habits Ruining Your Brain Health?

    The good news is that recurring nightmares are treatable. And the first-line medical treatment for nightmares has already been shown to decrease the build-up of abnormal proteins linked to Alzheimer’s disease. There have also been case reports showing improvements in memory and thinking skills after treating nightmares.

    These findings suggest that treating nightmares might help to slow cognitive decline and to prevent dementia from developing in some people. This will be an important avenue to explore in future research.

    The next steps for my research will include investigating whether nightmares in young people might also be linked to increased dementia risk. This could help to determine whether nightmares cause dementia, or whether they are simply an early sign in some people. I also plan to investigate whether other dream characteristics, such as how often we remember our dreams and how vivid they are, might also help to determine how likely people are to develop dementia in the future.

    This research might not only help to shed light on the relationship between dementia and dreaming, and provide new opportunities for earlier diagnoses – and possibly earlier interventions – but it may also shed new light on the nature and function of the mysterious phenomenon that we call dreaming.

    This article is taken from The Conversation, where it’s been published under a Creative Commons license.

    READ MORE: What Really Happens To Your Body (And Brain) On A Detox Diet?

    Abidemi Otaiku

    NIHR Academic Clinical Fellow in Neurology, University of Birmingham More