At just 16, Lizelle Knott faced her first cancer diagnosis – Non-Hodgkin’s B-cell Lymphoma. What followed was a rollercoaster of chemotherapy, surgeries and life-changing diagnoses. Now, at 43, she’s living with stage 4 metastatic breast cancer, but her story is anything but one of defeat. Instead, she’s built a sisterhood for others battling cancer, launched a clothing line designed to support those undergoing treatment and continues to be an inspiration to everyone who hears her story.
The Early Days of Battling Cancer
Non-Hodgkin’s B-cell Lymphoma was discovered in Lizelle’s chest cavity at age 16, constricting her windpipe and causing constant puffiness in her face. What had initially seemed like a reaction to skincare products soon revealed itself to be something far more sinister. Fresh from losing her father in a car accident the year before, the news shattered her family. But she faced it head-on, enduring 10 rounds of CHOP chemotherapy and coming out the other side – albeit with a GI Jane haircut, but in remission.
Life, however, had more hurdles in store for Lizelle. At 33, she was diagnosed with stage 2 Estrogen-Receptive Breast Cancer. A lump in her right breast confirmed her worst fears. She underwent a mastectomy, immediate reconstruction and six cycles of TC (Taxotere and Cyclophosphamide) chemotherapy. Once again, remission followed, but the reprieve was short-lived. “A few years later in 2017, during my routine three-monthly check-up, I was told the cancer had returned, this time in my liver. I moved from stage 2 to stage 4 in the blink of an eye – and my whole world was turned upside down,” recalls Lizelle. She adds: “At the time, I was busy with fertility treatment to attempt having a second baby. I had to give up on that dream of providing Grayson with a sibling.”
READ MORE: Run For The Girls: Conquer Miles & Support Breast Cancer Awareness #FLYGRLFLY
The Never-Ending Battle
Since that fateful moment in 2017, cancer has recurred more times than she can count. The disease metastasised to her scapula and vertebrae, leading to countless chemo cycles, radiation, liver resections and even the removal of her right kidney. It’s a list that seems endless, but she refuses to let it define her life.
“Instead, I choose to focus on what matters the most in my life – my son, Grayson, who was just 14 months old when he first heard the words ‘breast cancer,’” says Lizelle.
Today, Lizelle lives for Grayson – embracing the role of a mother, partner and businesswoman, despite the constant doctor’s visits, blood tests and treatments that have become part of her routine.
Her mantra? “Attitude is the difference between an ordeal and an adventure,” she says. It’s a perspective she clings to, even during the darkest times. While some days are undeniably tough, her positive outlook and the joy she finds in daily moments keep her going.
Navigating Treatment and Finding Strength
Each form of cancer has presented its own unique challenges. The chemo for lymphoma was particularly brutal, especially for a 16-year-old grappling with the trauma of losing her hair, recalls Lizelle. The hardships still didn’t deter her, she admits. “I managed to finish school and even became a prefect – which was one of my proudest achievements,” enthuses Lizelle.
When breast cancer arrived, she was determined to fight but now willing to lose her hair again. “I was adamant not to lose my hair for a second time. Not only for my mental well-being, but I also didn’t want Grayson dealing with a bald mommy at such a young age. I managed to save about 60 percent of my hair using the chemo cold cap system. If you bumped into me at the mall, you’d never know I was going through chemo,” she shares. Even with the chemo and radiation side effects having taken their toll on her, from cracked palms and feet to extreme fatigue, Lizelle always finds a way of forging ahead.
And then there were the liver resections – two of them – which she describes as the most painful experience she’s ever endured.
“I wouldn’t wish that experience on my worst enemy. But it’s a small price to pay if it means I get to spend another day with my boy and loved ones,” says Lizelle.
READ MORE: 5 First Steps To Take After An Early-Breast-Cancer Diagnosis
The Birth of ‘This Is Me’
One of the most significant ways she’s channelled her energy is through her brand, . Born out of a personal need for comfortable, yet empowering clothing to wear during chemo, the brand offers apparel for women on a similar journey as her. “I wanted to create outfits that were not just functional, featuring designs that accommodate chemo ports, but also stylish and motivational,” explains Lizelle. It’s evident that she’s poured her heart into this project, describing it as more than just a business but a lifeline for other women facing cancer.
And the rallying anthem behind her work? The song from the 2017 musical . She particularly loved the line: “I am bruised, I am brave, this is who I’m meant to be.” The leggings, emblazoned with the slogan down the leg serve as armour for the women who wear them – whether they’re heading to a chemo session or grabbing coffee with friends.
Empowering Others Through ‘This Is Me’
Her drive to empower others led her to design tops specifically for women with chemo ports. After experiencing the frustration of finding clothing items that offered easy access to her port without sacrificing her dignity, Lizelle saw an opportunity to make life a little easier for other women in her shoes. These port-friendly shirts and range of leggings aren’t just about function – they’re mainly for helping women feel good about themselves during one of the most challenging periods of their lives, she explains.
Lizelle also has a few new products in the pipeline – which include post-op robes and pyjamas designed with drain pockets, made from luxurious Armani satin. These items are as beautiful as they are practical, ensuring that women can feel both comforted and stylish after surgery. The chemo bags – customisable with handpicked essentials – will be another addition, offering thoughtful gifts for women facing treatment.
Parting shot
Her message to other women going through cancer? Find your “why.” In Lizelle’s case, her ‘why’ is Grayson. Whether it was planning his second birthday party during chemo or looking forward to another day spent with him, he’s always been the wind beneath her wings. “I want other women to know that it’s okay to have dark days and to feel overwhelmed. It’s also okay to be selfish with your time and energy to prioritise your health and well-being,” says Lizelle.
Through her own journey, she’s proving that life doesn’t end with a cancer diagnosis. There’s still joy, purpose, and, yes, adventure to be had, she reminds all of us. And through , she’s hoping to remind women everywhere that they are brave, beautiful and more than their scars. “I vowed to make it my mission to share my story and provide as much support as possible so that others didn’t feel as lonely on their cancer journeys,” notes Lizelle.
